B. In spite of, despite and although are all used to show a contrast
a. After ‘in spite of’ or ‘despite’, use a noun, a pronoun (this/ that/ what etc.) or ~ing. (e.g. We enjoyed our camping holiday in spite of the rain.)
b. Can say ‘in spite of the fact (that) ~‘ and ‘despite the fact (that) ~‘ (e.g. I didn’t get the job in spite of the fact (that) (= despite the fact (that)) I had the necessary qualifications.) (e.g. We went out in spite of the rain. vs. We didn’t go out because of the rain.)
B1. After ‘although’ we use a subject + verb (e.g. We went out although it was raining. vs. We didn’t go out because it was raining.)
a. I couldn’t sleep although I was very tired. (= despite being very tired. (not despite I was tired))
b. Sometime we use though instead of although. In spoken English we often use though at the end of a sentence. (e.g. The house isn’t very nice. I like the garden though. (= but I like the garden))
c. Even though is a stronger form of although. (e.g. We decided to buy the house even though we didn’t really have enough money.) Like although, even though is followed by a subject and a verb.